Potter has come under pressure after losing his last two Premier League matches to Arsenal and Brighton and Hove Albion, having gone unbeaten in his first nine games in charge.
Potter's task does not get any easier as Chelsea travel to Manchester City in the Carabao Cup on Wednesday.
Ahead of the game, Guardiola underlined how imperative it is for Chelsea to have patience for Potter.
"I'm not the right person to say that because it's not my business. But if Chelsea accepts my humble advice, with no intention, give him time and he will do well," Guardiola told reporters.
The City boss added: "I have a lot of admiration for his work. What he did at Brighton is beyond exceptional, and I'm pretty sure with time he will do a good job.
"I don't have any doubts about this. It's the same with Roberto De Zerbi at Brighton.
"When they start losing games, it's a question of time. If they are patient, he will have an impact in England and he will have it as Graham has done in this country.
"He's one of the best managers, from my point of view, we have in this league."
Chelsea appointed former Brighton boss Potter as manager in September after parting company with Thomas Tuchel.
