Pogba's contract at Old Trafford expires this summer and there are no indications that he wants to extend his stay at the club.
The 28-year-old, who is in his second spell with the Red Devils, has been linked with former club Juventus and Paris Saint Germain.
Coach Meddy, who is a Dubai-based fitness coach and counts Pogba among his clients, says the World Cup winner will definitely not sign a new contract when the current one runs out in the summer.
"Regarding Pogba, at the end of June, he will no longer be a Manchester player," he told calciomercato.com.
"I think it's right for him to look elsewhere. Maybe Manchester also want to renew themselves, and the most sensible thing is to separate.
"The time is coming to change and try new challenges, new emotions, new environments for both Pogba and Manchester, to try something different, and maybe they will both be happy.
"Right now, I think he's enjoying himself. They have a good team, especially since Ronaldo decided to return. The problem is the results aren't coming.
"A top player doesn't waste his time with minor competitions. He wants to be motivated to play for ambitious trophies."
An injury-hit campaign has seen Pogba make just 15 Premier League appearances for fifth-placed Manchester United this season, although he has still contributed one goal and nine assists.