The Red Devils sit second on the Premier League table 14 points behind Pep Guardiola’s men, who comfortably sit top with 65 points.
Solskjaer has admitted his side will only be focusing on breaking the unbeaten run of Manchester City instead of thinking of the league as they are far away from their rivals.
"Our focus is on this game, not where we are going to end up," said Solskjaer in his press conference.
"We want to be the best possible Man Utd and try to improve on last season, get to a final and win a trophy. They are ahead of us by a fair distance.
"I can only control what is happening at Man Utd, there are so many differences between the clubs. They are the only team ahead of us at the moment. It's a fantastic spell, with great form and 21 wins."
Manchester United have not scored in their last three games, but the Norwegian coach says his side could be affected by fixture congestion.
"We have had a week without scoring a goal, not six weeks’ of bad form," added Solskjaer.
"We beat Real Sociedad 4-0 and Southampton 9-0. The amount of games can have an effect.
"I am not buying into the narrative that we have had such a dip in form. We have defended well but we have lacked a little spark to score a goal."
