Lampard’s managerial bow at Chelsea ended in disappointment as the Blues succumbed to a humiliating 4-0 defeat at the hands of Manchester United at Old Trafford last Sunday despite being on top for large portions of the game and hitting the post twice.
The game at the Vodafone Park at Istanbul on Wednesday will give Lampard the chance to remedy Sunday’s disappointment and win a trophy he lost twice as a player with Chelsea.
Lampard captained Chelsea twice in the 2012 and 2013 UEFA Super Cup finals but lost on both occasions to Atletico Madrid and Bayern Munich respectively.
"I've had two great examples of a really important game that you don't win in two different ways and it makes you more determined to win it," he told UEFA.com.
"We need to be absolutely ready. It's a cup that the club desperately wants to win. I've never won it, a lot of players in there have never won it, so we have to give it everything.
"Going up against the team with the quality of Liverpool in a final is as tense as finals can be.
"You can lose finals, they're very tough. But what you cannot do is lose it on the premise that we weren’t prepared, or we didn't have that hunger or desire or everything you need to try and win a game of this magnitude.
"It's going to be one of my first competitive games as manager of this club. Every player in there needs to be aware of the importance of the game to this club and we have to give everything, because it's going to be tough.
"It's going to be tough, but we cannot walk off the pitch and think 'oh, we could've done that' or 'we missed that opportunity' or 'we weren't quite ready' or make any excuses for ourselves."