At the halfway stage of the title race this season, Arsenal hold a three-point lead at the top of the table with a game in hand.
They face champions Manchester City for the first time in the top flight at the Emirates Stadium on Wednesday and victory for either side will prove crucial in the grand scheme of things.
Wenger led Arsenal to their last league title in the 2003/2004 season.
With perennial title contenders Liverpool and Chelsea faltering this season, Man City remain Arsenal's main challengers for glory.
Arsenal have failed to pick maximum points in their last two games, allowing Man City to close in.
Wenger has charged Arsenal to take advantage this season as another opportunity to end their title drought might not come as easily again.
"You win it when you can win it and you don’t care too much about the rest you take the title and let the rest talk about it," the Frenchman told beIN Sports.
"I agree the conditions next season won’t be as favourable as they are now so let's not miss this opportunity. Arsenal has 51 points after 21 games, which is remarkable. I feel the usual threats are all out of the race. The only threat is City and even City is now not as dominant as they were last year or two years before, and I feel since the start of the season City was more vulnerable defensively than before."
