The Baggies currently occupy the final relegation spot on the championship table, having won just once in 13 games, drawing eight times.
Just four months after being dismissed as Newcastle United manager, Bruce joined West Brom in February as a replacement for Valerien Ismael but won just eight of 32 games in charge.
The sacking was announced in a club statement which read: “West Bromwich Albion have today parted company with Manager Steve Bruce.
“Backroom staff Steve Agnew, Stephen Clemence and Alex Bruce have also left The Hawthorns. The club would like to place on record its thanks to Steve Bruce and his coaching staff for their efforts since arriving in February.
“Under-21s coach Richard Beale will oversee first-team affairs on an interim basis, assisted by James Morrison and Gary Walsh. The process of recruiting a new Manager is now under way and an appointment will be confirmed in due course.”
West Brom are next in action against Reading this weekend.
