Manchester City and Liverpool played out an enthralling 2-2 draw at the Etihad Stadium on Sunday.
The result means that the champions remain a point ahead of the Reds with seven games left to play.
Kevin De Bruyne and Gabriel Jesus gave the hosts leads which were cancelled out each time by Diogo Jota and Sadio Mane.
Manchester City have a kinder run of games with five of their remaining games against sides currently in the bottom half of the table.
The two sides will meet again in the FA Cup semi-finals this weekend.
"Both teams wanted to try to win, we did everything we could but unfortunately we could not win," Guardiola told Sky Sports.
"I had the feeling we handed them a life, but listen Liverpool is a joy to watch and the threats they have in attack, how good they are, so no doubts about how difficult they are.
"But I think we performed really, really well, I'm so incredibly proud of my team. Now, both teams know with seven games left we have to win all of them, otherwise it will be over.
"In Anfield, we played an incredible first half and it was the same result, I had the feeling we missed an opportunity to get three points but it doesn't matter what happened this game, this was never going to be over.
"I would say the same with defeat, or victory, this was massive game to take advantage of, but we know what we have to do.
"Go to [Atletico] Madrid [in the Champions League quarter-final return leg], then FA Cup [semi-final against Liverpool] then back to the Premier League and win as many as possible.
"Seven games in the Premier League is a lot to play, it will be tough, I don't know whether we are going to win the title at the end of the season but to be in the game, like we played today, it makes me admire a lot to perform that way."
