In their first game since their disappointing exit to Real Madrid in the UEFA Champions League last Wednesday, PSG took out their frustrations on Bordeaux, beating them 3-0 at the Parc des Princes.
Goals from Kylian Mbappe, Neymar and Leandro Paredes took Pochettino's side 15 points clear at the top of the table.
However the PSG fans are still reeling from their latest European disappointment and they showed their displeasure by jeering Messi and Neymar when they had possession of the ball against Bordeaux.
Speaking at a media conference after the game, Pochettino said regarding the fans' jeering: "Nobody likes this background, it made me sad. Everyone who loves PSG after the Madrid disappointment is sad. I am saddened by what I experienced here today.
"We have all been affected. We understand the disappointment and frustration. We all experience this together, as a team. We have a responsibility to take responsibility for what happened. We share this disappointment of the supporters."
In an interview with Amazon Prime Video after the game, defender Presnel Kimpembe added: “Inevitably, we hear [the boos and whistles] anyway, even if we are focused, concentrated in our match.
"We understand their disappointment, we understand their hatred and their cries. Now we are professional, we must know how to remain so too. It is now that we must raise our heads and be able to move forward in order to be able to win this league."