Liverpool got the better of Tottenham in the UEFA Champions League final at the Wanda Metropolitano last season and Sunday’s meeting will represent the first meeting between them since.
The Reds remain the only unbeaten side in the league this season, winning eight and drawing one of their nine games to lead the table while Tottenham have struggled to hit the highs of last season with just three wins.
Kane failed to score in three games against Liverpool last season but the England captain has struck five times against the Reds in previous campaigns and is undaunted by the task of facing UEFA’s Player of the Year and his colleagues.
"Van Dijk is a great defender but he's not invincible and Liverpool are not invincible," said Kane, who battled back from an ankle injury to feature in the Champions League final.
"We just have to concentrate on ourselves. Any team can be beaten on any day and we just have to try to make sure we do that at Anfield.
"As a striker, it's not just one-v-one on the pitch; there's a lot that goes into it. Van Dijk is an amazing defender and he has had a fantastic couple of years at Liverpool.
"From my point of view, it's just about playing my game and making my movements, doing my runs and trying to get on the scoresheet, trying to get assists.
"At the end of the day it's a team game, so we all have to be on it with each other and that's the main aim."
