Fofana had to leave the pitch on a stretcher after Nino's tackle sent him into critical condition.
Showing remorse for his act, the 20-year-old has rendered a heart-warming apology to French defender Fofana.
"I am writing to publicly apologise, having already done so privately with him," Nino wrote on Instagram.
"At no time was it my intention to harm him, as unfortunately happened.
"I sincerely hope that he has a speedy recovery and can return to the pitch as soon as possible to continue showing that he is a footballer of the highest level."
According to Leicester City boss Brendan Rodgers, Fofana is expected to have another scan to reveal how long he will spend on the sidelines, insisting Villarreal manager Unai Emery had already apologised for the unfortunate incident.
"He's going to be a huge loss for us," said Rodgers.
"It was a horrendous challenge and we're obviously devastated for him.
"The medical team looked after him and the trauma doctor had to put his ankle back in place before went to hospital.
"The ankle was so swollen it was not safe to be looked at so he will have another scan, which should give a clear indication of how long he will be out."
Fofana’s injury is a massive blow to Leicester City as they prepare for the upcoming season after finishing 5th in the league log last term.
Leicester City will play Manchester City in the Community Shield on Saturday, before they open their league campaign at home to Wolves on August 14.
