Reus has been feeling the effects after enjoying a largely injury-free 2020/2021 season, making 48 appearances across all competitions and scoring 10 goals.
The 31-year-old has helped Dortmund qualify for next season’s Champions League and also skippered his side to the DFB-Pokal trophy with a 4-1 win over RB Leipzig last week.
Having battled a host of injuries in recent seasons, Reus reckons he will be better served taking a summer break than turning out for Germany at EURO 2020.
"After a complicated, exhausting and, in the end, ‘thank God’ successful season, I decided, together with the national team coach not to go to the European Championship," Reus stated on Instagram.
“This decision was very difficult for me because I am always full of pride when I am allowed to appear for my country.
“But after a very intense year for me personally and achieving my goals at BVB, I made the decision to give my body time to recover!
“I will make good use of the break in order to be able to start the new season optimally! I wish 'Jogi' and our team all the best for the Euros and I will cheer as a fan and keep my fingers crossed.”
Reus has won 44 caps for Germany, scoring 13 goals.