Barcelona bounced back from last week’s disappointing 2-1 defeat to Granada by beating Valencia 3-2 on Sunday to move within two points of leaders Atletico Madrid.
With just four games of the season remaining, whoever comes out on top on Saturday stands a better chance of securing the title, although champions Real Madrid are also in with a chance as they also sit two points behind Atletico Madrid.
"We have won a game after the unexpected defeat [vs Granada] to continue fighting until the end," Pique told Movistar. "We are still there in the fight. We are there, that was the goal.
"We would like to be able to close the games earlier, they are dynamics and things that could happen. You have to analyze goal by goal, they shoot us less, but the problem is that all those shoots go inside. Thursday's defeat did a lot of damage, but winning against Villarreal and Valencia gives us confidence.
"We prepare us for the Atlético Madrid game with the only idea of winning. It's in our hands. We have to win, there's no other option."