Goals from Mason Mount and Ben Chilwell saw the Premier League outfit take control of the tie at the Ramon Sanchez Pizjuan in Seville last week.
The second leg of the quarterfinal encounter takes place at the same stadium later on Tuesday because of coronavirus restrictions.
Conceicao believes his side have enough quality to turn the tie around against Thomas Tuchel’s men and is drawing inspiration from the many memorable Champions League comebacks that have occurred over the years.
"There are many moments overs the years that can be examples of overcoming and believing," said the Porto head coach.
"We are confident. We know that we are going to face a difficult obstacle, but we are here to give the answer that we have to give. The feeling of representing this historic club and its DNA is always on the pitch."
He added: "We have to be a compact, cohesive team. It is necessary to score goals, but also not to suffer.
"In the first leg we played a good game, but it was not good enough. If it were, we would have won the game. We will try to improve even more what was a good performance by the team.
"Over 90 minutes for FC Porto it requires the ability to believe and be resilient. We always try to enter with that spirit. We are ready to go to the fight and to fight."
