Ighalo made a surprise switch from Chinese Super League side Shanghai Shenhua to Manchester United on the last day of the winter transfer window last season.
An impressive start to life at Old Trafford, during which Ighalo scored four times in his first eight appearances, saw the former Nigeria international’s deal extended till the end of January 2021.
However, the arrival of Edinson Cavani at the start of the current campaign has limited Ighalo’s first team chances as he has made just four appearances in all competitions this season.
"It's so hard to see this dream come to an end," Ighalo wrote on social media. "But I give God the glory for helping me fulfill this lifelong [sic] dream of putting on a Manchester United shirt as a player and represent this great club, it was indeed an honor I will forever cherish and be grateful for.
"To the manager I say thank you for trusting and believing in me when many did not, to my amazing team-mates I will miss you guys, it was always fun and a time I look [sic] forward to training and spending time with all of you. And I pray we win the LEAGUE and FA cup this year.
"To the best fans in the world (the Manchester United fans) we have missed you, but we hear your voices cheering us on from afar, we can't wait to have you all back on the stands.
"I'm still and would remain a MANCHESTER UNITED FAN forever. Once a Red, always a Red."