Guardiola led City to an unprecedented treble comprising the Premier League, FA Cup and UEFA Champions League last season.
The Citizens will begin their title defence away at newly-promoted Burnley on Friday.
In captain Ilkay Gundogan and Riyad Mahrez, Manchester City have lost two stalwarts from last season's heroics but have also brought in Croatian pair Mateo Kovacic and Josko Gvardiol to augment the squad.
“We are going to drop that’s for sure,” said Guardiola, whose side begin their quest for a sixth domestic title in seven years at Burnley on Friday.
“It’s inevitable a little bit. We’ll try to avoid it as much as possible. Now it’s (about) not dropping too much – staying there, staying there, (being) close to our rivals.
“Then try to, in the last four, five, or six months, try to do what we have done every season. I don’t want to do it now. That is my feeling.
“Now, (it would be a) big mistake thinking about trophies and titles – big mistake.”
