Toure is leaving his role as an under-16 coach at Tottenham Hotspurs, where he has spent the last 18 months.
The 40-year-old has also held assistant coaching roles at Ukrainian side Olimpik Donetsk and Russian outfit Akhmat Grozny in recent seasons.
Toure wrote on Twitter: "I am delighted to share that I will be taking on the role of assistant coach at Standard de Liege. It's an honour to join the club and I am looking forward to working with head coach Carl Hoefkens.
"I would like to thank everyone at the Tottenham Hotspur Academy for their support in the 18 months I spent with the club. A special mention to Dean Rastrick, Chris Powell and all the young players. Thank you."
Toure, who is a four-time African footballer of the year, spent eight seasons with Manchester City where he won three Premier League titles, one FA Cup and two League Cups.
Toure also played for AS Monaco and Barcelona, where he won the 2009 UEFA Champions League and two La Liga titles.
He was a member of the Ivory Coast national team that beat Ghana on penalties to win the 2015 African Cup of Nations.
