The former goalkeeper had two spells at the Ramon Sanchez Pizjuan stadium as sporting director between 2000 and 2023, a period during which Sevilla won the UEFA Cup/Europa League seven times.
Three of those continental triumphs came under current Aston Villa manager Unai Emery.
Under Emery's guidance, Aston Villa went from relegation candidates to seal a spot in next season's Europa Conference League, after taking over from Steven Gerrard in October.
Monchi, who left Sevilla in 2017 and became sporting director at Roma before returning to the Ramon Sanchez Pizjuan Stadium two years later, said on Villa’s official website: “I am very excited to join Aston Villa, a great project which is striving for excellence from the Under-9s to the top level, and I completely share the vision of Mr Sawiris and Mr Edens (owners Nassef Sawiris and Wes Edens).
“I am also delighted and can’t wait to work with Unai Emery again, one of the best managers in football.
“After enjoying so many years with Sevilla and winning several European trophies with my life-long club, I look forward to building on the recent successes at Aston Villa and ensuring this colossal club continues to grow and improve.”
Villa chairman Sawiris said: “We are delighted to have Monchi joining us in this new position that consolidates all football responsibilities at the group.
“Alongside Unai and his staff, Monchi’s arrival will add to the world class team we are assembling both on and off the pitch. He is, like Unai Emery, a serial winner.
“With the appointment of Chris Heck on the business side, this new structure will ensure that the club is firing on all cylinders on the commercial side in addition to the football side to ensure that the club’s model is sustainable and positioned well to meet our growing ambitions.”