Aubameyang made his debut for the Gabon national team back in 2009 and appeared 72 times for his country, becoming their all-time top scorer with 30 goals.
The Barcelona striker has made the announcement just weeks before the commencement of the qualifiers for the 2023 Africa Cup of Nations.
Aubameyang was part of the Gabon team for the AFCON 2021 held in January/February but did not play at the tournament after suffering complications from a positive Coronavirus infection.
"After 13 years of pride in representing my country, I announce that I am ending my international career," the 32-year-old wrote in an open letter to Gabon fans.
"I would like to thank the Gabonese people and all those who have supported me in the good like the bad times.
"I will keep a lot of good memories like the day I made my debut at romnisports, or the day I came back from Nigeria with the African Ballon d'Or.
"Sharing it with all the people was an unforgettable moment. I thank our President, his Excellency Ali Bongo Ondimba who has always supported the Panthers and has always worked for football to evolve in our country.
"I would also like to thank all my coaches, staff and the players that I have come across during this career.
"Finally, I thank my father who gave me the desire to do like him, hoping to have made him proud by wearing our colours."
