The Azzurris have started EURO 2020 with back-to-back wins over Turkey and Switzerland, and have already secured their place in the knockout rounds of the competition but they will face a Welsh side brimming with confidence after a convincing 2-0 win over Turkey last time out.
Mancini spent three-and-a-half years in England as Manchester City manager and battled former Premier League side Stoke City on numerous occasions including a 1-0 win over the Potters in the 2011 FA Cup final.
Mancini boasts four wins and four draws from eight Premier League outings against Stoke City.
"Stoke had a very tough style of play, they were a very tough nut to crack," Mancini said on Saturday.
"It will be a very difficult match from a physical perspective because they are a powerful side like Stoke, but they are also very technical.
"Wales have players like [Joe] Allen, [Gareth] Bale and [Daniel] James. They have got some quality and skillful players."
Italy will go into the game on the back of a 10-game winning run in all competitions, having not conceded a goal in that time.
