Spurs, who are striving to get back to the top four after a recent bad run, put up a stellar performance to move sixth on the Premier League table.
In-form Gareth Bale put the hosts ahead inside 25 minutes but the South Londoners pulled parity on the cusp of halftime.
Bale re-established Mourinho’s men’s lead four minutes after the interval before Harry Kane scored on 52 and 76 minutes respectively to put the game beyond the Eagles.
Four goals against Crystal Palace brought up their century for the season in all competitions, and Mourinho was quick to hit out at his critics right after the game.
"After three victories in the same week. If the stats I was given are correct - 100 goals scored in the season, which for a very defensive team, a very negative team, is not bad,” the former Chelsea and Manchester United coach told Sky Sports.
"Playing with happiness, with good self-esteem, we have lots of qualities. Of course it is a privilege to have such a very good group of players.
"It was a good week for us. Three matches, nine points, and in the coming days when we play a crucial match in the Europa, and against Arsenal, nothing could be better for us than to win nine points this week."
