The Primeira Liga was suspended on March 12, with FC Porto sitting a point clear of rivals Benfica after 24 games.
Last month, Portugal prime minister Antonio Costa gave the league the green light to resume behind closed doors from May 30.
A statement released by the league authorities, Liga Portugal, read: "Over the past few days, various entities have carried out successive alignment meetings so that the recovery can take place safely and with all the protection measures that mitigate the risks of returning to the activity.
"It is anticipated that this joint work by DGS [Directorate-General of Health of Portugal], FPF [Portuguese Football Federation] and Liga Portugal will serve as a model for the resumption of other economic activities, with the aim of this professional competition providing an example of the good practices that this pandemic imposes on us.
"In order to ensure that the stadiums are strictly inspected and medical tests are carried out on all professionals involved in the games and their organisation, the date of June 4, 2020 is set for the first game of the 25th round of the Liga NOS."
All 18 clubs in the league have 10 games left to play.
Portugal has so far recorded 27,913 cases of Covid-19 which has resulted in 1,163 deaths.
