The two teams were issued with the alert in the wake of recent heavy rains and flooding in the principality.
The Stade Louis II in Monaco was set to play hosts to the two sides but a new date will now have to be found for the game.
Olympique Marseille’s 2-1 win over Brest on Friday cut PSG’s lead at the top of the table to five points and they were looking to reestablish their eight-point lead with victory over Monaco.
“Following a decision by the Monaco authorities, the game between Monaco and Paris Saint-Germain, scheduled today at 21:00 (8pm GMT/3pm ET), is cancelled and will be played at a later date because of the weather conditions,” Monaco said in a statement.
"This decision comes as the departments of Var and Alpes-Maritimes are placed in red alert for rain and floods. The Competition Commission of the LFP will fix the date of the meeting at a later date.
"AS Monaco will soon be providing the ticketing information following this postponement."
The two teams have midweek league games on Wednesday as Thomas Tuchel’s side host Nantes at the Parc des Princes while 14th placed AS Monaco are away at bottom side Toulouse.
